The Genomic Landscape of Juvenile Myelomonocytic Leukemia
Identifieur interne : 001755 ( Main/Exploration ); précédent : 001754; suivant : 001756The Genomic Landscape of Juvenile Myelomonocytic Leukemia
Auteurs : Elliot Stieglitz [États-Unis] ; Amaro N. Taylor-Weiner [États-Unis] ; Tiffany Y. Chang [États-Unis] ; Laura C. Gelston [États-Unis] ; Yong-Dong Wang [États-Unis] ; Tali Mazor [États-Unis] ; Emilio Esquivel [États-Unis] ; Ariel Yu [États-Unis] ; Sara Seepo [États-Unis] ; Scott Olsen [États-Unis] ; Mara Rosenberg [États-Unis] ; Sophie L. Archambeault [États-Unis] ; Ghada Abusin [États-Unis] ; Kyle Beckman [États-Unis] ; Patrick A. Brown [États-Unis] ; Michael Briones [États-Unis] ; Benjamin Carcamo [États-Unis] ; Todd Cooper [États-Unis] ; Gary V. Dahl [États-Unis] ; Peter D. Emanuel [États-Unis] ; Mark N. Fluchel [États-Unis] ; Rakesh K. Goyal [États-Unis] ; Robert J. Hayashi [États-Unis] ; Johann Hitzler [Canada] ; Christopher Hugge [États-Unis] ; Y. Lucy Liu [États-Unis] ; Yoav H. Messinger [États-Unis] ; Donald H. Mahoney [États-Unis] ; Philip Monteleone [États-Unis] ; Eneida R. Nemecek [États-Unis] ; Philip A. Roehrs [États-Unis] ; Reuven J. Schore [États-Unis] ; Kimo C. Stine [États-Unis] ; Clifford M. Takemoto [États-Unis] ; Jeffrey A. Toretsky [États-Unis] ; Joseph F. Costello [États-Unis] ; Adam B. Olshen [États-Unis] ; Chip Stewart [États-Unis] ; Yongjin Li [États-Unis] ; Jing Ma [États-Unis] ; Robert B. Gerbing [États-Unis] ; Todd A. Alonzo [États-Unis] ; Gad Getz [États-Unis] ; Tanja Gruber [États-Unis] ; Todd Golub [États-Unis] ; Kimberly Stegmaier [États-Unis] ; Mignon L. Loh [États-Unis]Source :
- Nature genetics [ 1061-4036 ] ; 2015.
Abstract
Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative neoplasm (MPN) of childhood with a poor prognosis. Mutations in
Url:
DOI: 10.1038/ng.3400
PubMed: 26457647
PubMed Central: 4626387
Affiliations:
- Canada, États-Unis
- Arkansas, Californie, Caroline du Nord, District de Columbia, Géorgie (États-Unis), Iowa, Massachusetts, Minnesota, Missouri (État), Oregon, Pennsylvanie, Tennessee, Texas, Utah, Washington (État)
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 004710
- to stream Pmc, to step Curation: 004709
- to stream Pmc, to step Checkpoint: 000E16
- to stream Ncbi, to step Merge: 007A08
- to stream Ncbi, to step Curation: 007A08
- to stream Ncbi, to step Checkpoint: 007A08
- to stream Main, to step Merge: 001757
- to stream Main, to step Curation: 001755
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Genomic Landscape of Juvenile Myelomonocytic Leukemia</title><author><name sortKey="Stieglitz, Elliot" sort="Stieglitz, Elliot" uniqKey="Stieglitz E" first="Elliot" last="Stieglitz">Elliot Stieglitz</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Taylor Weiner, Amaro N" sort="Taylor Weiner, Amaro N" uniqKey="Taylor Weiner A" first="Amaro N." last="Taylor-Weiner">Amaro N. Taylor-Weiner</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Chang, Tiffany Y" sort="Chang, Tiffany Y" uniqKey="Chang T" first="Tiffany Y." last="Chang">Tiffany Y. Chang</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Gelston, Laura C" sort="Gelston, Laura C" uniqKey="Gelston L" first="Laura C." last="Gelston">Laura C. Gelston</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Wang, Yong Dong" sort="Wang, Yong Dong" uniqKey="Wang Y" first="Yong-Dong" last="Wang">Yong-Dong Wang</name><affiliation wicri:level="2"><nlm:aff id="A3">Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Computational Biology, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation></author><author><name sortKey="Mazor, Tali" sort="Mazor, Tali" uniqKey="Mazor T" first="Tali" last="Mazor">Tali Mazor</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Neurological Surgery, University of California, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Neurological Surgery, University of California, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Esquivel, Emilio" sort="Esquivel, Emilio" uniqKey="Esquivel E" first="Emilio" last="Esquivel">Emilio Esquivel</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Yu, Ariel" sort="Yu, Ariel" uniqKey="Yu A" first="Ariel" last="Yu">Ariel Yu</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Seepo, Sara" sort="Seepo, Sara" uniqKey="Seepo S" first="Sara" last="Seepo">Sara Seepo</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Olsen, Scott" sort="Olsen, Scott" uniqKey="Olsen S" first="Scott" last="Olsen">Scott Olsen</name><affiliation wicri:level="2"><nlm:aff id="A5">Hartwell Center for Bioinformatics and Biotechnology, St. Jude Children's Research Hospital, Memphis, TN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Hartwell Center for Bioinformatics and Biotechnology, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation></author><author><name sortKey="Rosenberg, Mara" sort="Rosenberg, Mara" uniqKey="Rosenberg M" first="Mara" last="Rosenberg">Mara Rosenberg</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Archambeault, Sophie L" sort="Archambeault, Sophie L" uniqKey="Archambeault S" first="Sophie L." last="Archambeault">Sophie L. Archambeault</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Abusin, Ghada" sort="Abusin, Ghada" uniqKey="Abusin G" first="Ghada" last="Abusin">Ghada Abusin</name><affiliation wicri:level="2"><nlm:aff id="A6">Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Iowa</region></placeName><wicri:cityArea>Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City</wicri:cityArea></affiliation></author><author><name sortKey="Beckman, Kyle" sort="Beckman, Kyle" uniqKey="Beckman K" first="Kyle" last="Beckman">Kyle Beckman</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Brown, Patrick A" sort="Brown, Patrick A" uniqKey="Brown P" first="Patrick A." last="Brown">Patrick A. Brown</name><affiliation wicri:level="2"><nlm:aff id="A7">Department of Pediatrics, The Johns Hopkins Hospital, Baltimore, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Pediatrics, The Johns Hopkins Hospital, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Briones, Michael" sort="Briones, Michael" uniqKey="Briones M" first="Michael" last="Briones">Michael Briones</name><affiliation wicri:level="2"><nlm:aff id="A8">Department of Pediatrics, Emory University School of Medicine, Aflac Cancer and Blood Disorder Center, Atlanta, GA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Department of Pediatrics, Emory University School of Medicine, Aflac Cancer and Blood Disorder Center, Atlanta</wicri:cityArea></affiliation></author><author><name sortKey="Carcamo, Benjamin" sort="Carcamo, Benjamin" uniqKey="Carcamo B" first="Benjamin" last="Carcamo">Benjamin Carcamo</name><affiliation wicri:level="2"><nlm:aff id="A9">Department of Pediatrics, Texas Tech University, El Paso, TX</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Department of Pediatrics, Texas Tech University, El Paso</wicri:cityArea></affiliation></author><author><name sortKey="Cooper, Todd" sort="Cooper, Todd" uniqKey="Cooper T" first="Todd" last="Cooper">Todd Cooper</name><affiliation wicri:level="2"><nlm:aff id="A10">Department of Pediatrics, Seattle Children's Hospital, Seattle, WA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Washington (État)</region></placeName><wicri:cityArea>Department of Pediatrics, Seattle Children's Hospital, Seattle</wicri:cityArea></affiliation></author><author><name sortKey="Dahl, Gary V" sort="Dahl, Gary V" uniqKey="Dahl G" first="Gary V." last="Dahl">Gary V. Dahl</name><affiliation wicri:level="2"><nlm:aff id="A11">Department of Pediatrics, Stanford School of Medicine, Stanford, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Stanford School of Medicine, Stanford</wicri:cityArea></affiliation></author><author><name sortKey="Emanuel, Peter D" sort="Emanuel, Peter D" uniqKey="Emanuel P" first="Peter D." last="Emanuel">Peter D. Emanuel</name><affiliation wicri:level="2"><nlm:aff id="A12">Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Arkansas</region></placeName><wicri:cityArea>Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock</wicri:cityArea></affiliation></author><author><name sortKey="Fluchel, Mark N" sort="Fluchel, Mark N" uniqKey="Fluchel M" first="Mark N." last="Fluchel">Mark N. Fluchel</name><affiliation wicri:level="2"><nlm:aff id="A13">Department of Pediatric Hematology Oncology, University of Utah, Salt Lake City, UT</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Utah</region></placeName><wicri:cityArea>Department of Pediatric Hematology Oncology, University of Utah, Salt Lake City</wicri:cityArea></affiliation></author><author><name sortKey="Goyal, Rakesh K" sort="Goyal, Rakesh K" uniqKey="Goyal R" first="Rakesh K." last="Goyal">Rakesh K. Goyal</name><affiliation wicri:level="2"><nlm:aff id="A14">Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh</wicri:cityArea></affiliation></author><author><name sortKey="Hayashi, Robert J" sort="Hayashi, Robert J" uniqKey="Hayashi R" first="Robert J." last="Hayashi">Robert J. Hayashi</name><affiliation wicri:level="2"><nlm:aff id="A15">Department of Pediatrics, Washington University School of Medicine, St. Louis, MO</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Missouri (État)</region></placeName><wicri:cityArea>Department of Pediatrics, Washington University School of Medicine, St. Louis</wicri:cityArea></affiliation></author><author><name sortKey="Hitzler, Johann" sort="Hitzler, Johann" uniqKey="Hitzler J" first="Johann" last="Hitzler">Johann Hitzler</name><affiliation wicri:level="1"><nlm:aff id="A16">Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Hugge, Christopher" sort="Hugge, Christopher" uniqKey="Hugge C" first="Christopher" last="Hugge">Christopher Hugge</name><affiliation wicri:level="2"><nlm:aff id="A17">Pediatric Hematology Oncology, SSM Cardinal Glennon Children's Medical Center, Saint Louis, MO</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Missouri (État)</region></placeName><wicri:cityArea>Pediatric Hematology Oncology, SSM Cardinal Glennon Children's Medical Center, Saint Louis</wicri:cityArea></affiliation></author><author><name sortKey="Liu, Y Lucy" sort="Liu, Y Lucy" uniqKey="Liu Y" first="Y. Lucy" last="Liu">Y. Lucy Liu</name><affiliation wicri:level="2"><nlm:aff id="A12">Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Arkansas</region></placeName><wicri:cityArea>Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock</wicri:cityArea></affiliation></author><author><name sortKey="Messinger, Yoav H" sort="Messinger, Yoav H" uniqKey="Messinger Y" first="Yoav H." last="Messinger">Yoav H. Messinger</name><affiliation wicri:level="2"><nlm:aff id="A18">Division of Pediatric Hematology Oncology, Children's Hospitals and Clinics of Minnesota, Minneapolis, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Division of Pediatric Hematology Oncology, Children's Hospitals and Clinics of Minnesota, Minneapolis</wicri:cityArea></affiliation></author><author><name sortKey="Mahoney, Donald H" sort="Mahoney, Donald H" uniqKey="Mahoney D" first="Donald H." last="Mahoney">Donald H. Mahoney</name><affiliation wicri:level="2"><nlm:aff id="A19">Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston</wicri:cityArea></affiliation></author><author><name sortKey="Monteleone, Philip" sort="Monteleone, Philip" uniqKey="Monteleone P" first="Philip" last="Monteleone">Philip Monteleone</name><affiliation wicri:level="2"><nlm:aff id="A20">Pediatric Hematology Oncology, Pediatric Specialists of Lehigh Valley Hospital, Bethlehem, PA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Pediatric Hematology Oncology, Pediatric Specialists of Lehigh Valley Hospital, Bethlehem</wicri:cityArea></affiliation></author><author><name sortKey="Nemecek, Eneida R" sort="Nemecek, Eneida R" uniqKey="Nemecek E" first="Eneida R." last="Nemecek">Eneida R. Nemecek</name><affiliation wicri:level="2"><nlm:aff id="A21">Pediatric Bone Marrow Transplant Program, Oregon Health & Science University, Portland, OR</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Oregon</region></placeName><wicri:cityArea>Pediatric Bone Marrow Transplant Program, Oregon Health & Science University, Portland</wicri:cityArea></affiliation></author><author><name sortKey="Roehrs, Philip A" sort="Roehrs, Philip A" uniqKey="Roehrs P" first="Philip A." last="Roehrs">Philip A. Roehrs</name><affiliation wicri:level="2"><nlm:aff id="A22">Department of Pediatrics, University of North Carolina at Chapel Hill, NC</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Department of Pediatrics, University of North Carolina at Chapel Hill</wicri:cityArea></affiliation></author><author><name sortKey="Schore, Reuven J" sort="Schore, Reuven J" uniqKey="Schore R" first="Reuven J." last="Schore">Reuven J. Schore</name><affiliation wicri:level="2"><nlm:aff id="A23">Division of Pediatric Oncology, Children's National Medical Center, Washington, DC</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">District de Columbia</region></placeName><wicri:cityArea>Division of Pediatric Oncology, Children's National Medical Center, Washington</wicri:cityArea></affiliation></author><author><name sortKey="Stine, Kimo C" sort="Stine, Kimo C" uniqKey="Stine K" first="Kimo C." last="Stine">Kimo C. Stine</name><affiliation wicri:level="2"><nlm:aff id="A24">Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Arkansas</region></placeName><wicri:cityArea>Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock</wicri:cityArea></affiliation></author><author><name sortKey="Takemoto, Clifford M" sort="Takemoto, Clifford M" uniqKey="Takemoto C" first="Clifford M." last="Takemoto">Clifford M. Takemoto</name><affiliation wicri:level="2"><nlm:aff id="A7">Department of Pediatrics, The Johns Hopkins Hospital, Baltimore, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Pediatrics, The Johns Hopkins Hospital, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Toretsky, Jeffrey A" sort="Toretsky, Jeffrey A" uniqKey="Toretsky J" first="Jeffrey A." last="Toretsky">Jeffrey A. Toretsky</name><affiliation wicri:level="2"><nlm:aff id="A25">Department of Pediatrics, Georgetown University, Washington, DC</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">District de Columbia</region></placeName><wicri:cityArea>Department of Pediatrics, Georgetown University, Washington</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A26">Department of Oncology, Georgetown University, Washington, DC</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">District de Columbia</region></placeName><wicri:cityArea>Department of Oncology, Georgetown University, Washington</wicri:cityArea></affiliation></author><author><name sortKey="Costello, Joseph F" sort="Costello, Joseph F" uniqKey="Costello J" first="Joseph F." last="Costello">Joseph F. Costello</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Neurological Surgery, University of California, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Neurological Surgery, University of California, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Olshen, Adam B" sort="Olshen, Adam B" uniqKey="Olshen A" first="Adam B." last="Olshen">Adam B. Olshen</name><affiliation wicri:level="2"><nlm:aff id="A27">Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A28">Department of Epidemiology and Biostatistics, University of California, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Epidemiology and Biostatistics, University of California, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Stewart, Chip" sort="Stewart, Chip" uniqKey="Stewart C" first="Chip" last="Stewart">Chip Stewart</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Li, Yongjin" sort="Li, Yongjin" uniqKey="Li Y" first="Yongjin" last="Li">Yongjin Li</name><affiliation wicri:level="2"><nlm:aff id="A3">Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Computational Biology, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation></author><author><name sortKey="Ma, Jing" sort="Ma, Jing" uniqKey="Ma J" first="Jing" last="Ma">Jing Ma</name><affiliation wicri:level="2"><nlm:aff id="A29">Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Pathology, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation></author><author><name sortKey="Gerbing, Robert B" sort="Gerbing, Robert B" uniqKey="Gerbing R" first="Robert B." last="Gerbing">Robert B. Gerbing</name><affiliation wicri:level="2"><nlm:aff id="A30">Department of Statistics, Children's Oncology Group, Monrovia, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Statistics, Children's Oncology Group, Monrovia</wicri:cityArea></affiliation></author><author><name sortKey="Alonzo, Todd A" sort="Alonzo, Todd A" uniqKey="Alonzo T" first="Todd A." last="Alonzo">Todd A. Alonzo</name><affiliation wicri:level="2"><nlm:aff id="A31">Keck School of Medicine, University of Southern California, Los Angeles, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Keck School of Medicine, University of Southern California, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Getz, Gad" sort="Getz, Gad" uniqKey="Getz G" first="Gad" last="Getz">Gad Getz</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A32">Harvard Medical School, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Harvard Medical School, Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A33">Department of Pathology and Cancer Center, Massachusetts General Hospital, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Pathology and Cancer Center, Massachusetts General Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Gruber, Tanja" sort="Gruber, Tanja" uniqKey="Gruber T" first="Tanja" last="Gruber">Tanja Gruber</name><affiliation wicri:level="2"><nlm:aff id="A29">Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Pathology, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A34">Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Oncology, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation></author><author><name sortKey="Golub, Todd" sort="Golub, Todd" uniqKey="Golub T" first="Todd" last="Golub">Todd Golub</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A35">Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A36">Division of Hematology/Oncology, Boston Children's Hospital and Harvard Medical School, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Hematology/Oncology, Boston Children's Hospital and Harvard Medical School, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Stegmaier, Kimberly" sort="Stegmaier, Kimberly" uniqKey="Stegmaier K" first="Kimberly" last="Stegmaier">Kimberly Stegmaier</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A35">Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A36">Division of Hematology/Oncology, Boston Children's Hospital and Harvard Medical School, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Hematology/Oncology, Boston Children's Hospital and Harvard Medical School, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Loh, Mignon L" sort="Loh, Mignon L" uniqKey="Loh M" first="Mignon L." last="Loh">Mignon L. Loh</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A37">Department of Pediatrics, Benioff Children's Hospital, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26457647</idno><idno type="pmc">4626387</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626387</idno><idno type="RBID">PMC:4626387</idno><idno type="doi">10.1038/ng.3400</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">004710</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">004710</idno><idno type="wicri:Area/Pmc/Curation">004709</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">004709</idno><idno type="wicri:Area/Pmc/Checkpoint">000E16</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000E16</idno><idno type="wicri:Area/Ncbi/Merge">007A08</idno><idno type="wicri:Area/Ncbi/Curation">007A08</idno><idno type="wicri:Area/Ncbi/Checkpoint">007A08</idno><idno type="wicri:doubleKey">1061-4036:2015:Stieglitz E:the:genomic:landscape</idno><idno type="wicri:Area/Main/Merge">001757</idno><idno type="wicri:Area/Main/Curation">001755</idno><idno type="wicri:Area/Main/Exploration">001755</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Genomic Landscape of Juvenile Myelomonocytic Leukemia</title><author><name sortKey="Stieglitz, Elliot" sort="Stieglitz, Elliot" uniqKey="Stieglitz E" first="Elliot" last="Stieglitz">Elliot Stieglitz</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Taylor Weiner, Amaro N" sort="Taylor Weiner, Amaro N" uniqKey="Taylor Weiner A" first="Amaro N." last="Taylor-Weiner">Amaro N. Taylor-Weiner</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Chang, Tiffany Y" sort="Chang, Tiffany Y" uniqKey="Chang T" first="Tiffany Y." last="Chang">Tiffany Y. Chang</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Gelston, Laura C" sort="Gelston, Laura C" uniqKey="Gelston L" first="Laura C." last="Gelston">Laura C. Gelston</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Wang, Yong Dong" sort="Wang, Yong Dong" uniqKey="Wang Y" first="Yong-Dong" last="Wang">Yong-Dong Wang</name><affiliation wicri:level="2"><nlm:aff id="A3">Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Computational Biology, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation></author><author><name sortKey="Mazor, Tali" sort="Mazor, Tali" uniqKey="Mazor T" first="Tali" last="Mazor">Tali Mazor</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Neurological Surgery, University of California, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Neurological Surgery, University of California, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Esquivel, Emilio" sort="Esquivel, Emilio" uniqKey="Esquivel E" first="Emilio" last="Esquivel">Emilio Esquivel</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Yu, Ariel" sort="Yu, Ariel" uniqKey="Yu A" first="Ariel" last="Yu">Ariel Yu</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Seepo, Sara" sort="Seepo, Sara" uniqKey="Seepo S" first="Sara" last="Seepo">Sara Seepo</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Olsen, Scott" sort="Olsen, Scott" uniqKey="Olsen S" first="Scott" last="Olsen">Scott Olsen</name><affiliation wicri:level="2"><nlm:aff id="A5">Hartwell Center for Bioinformatics and Biotechnology, St. Jude Children's Research Hospital, Memphis, TN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Hartwell Center for Bioinformatics and Biotechnology, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation></author><author><name sortKey="Rosenberg, Mara" sort="Rosenberg, Mara" uniqKey="Rosenberg M" first="Mara" last="Rosenberg">Mara Rosenberg</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Archambeault, Sophie L" sort="Archambeault, Sophie L" uniqKey="Archambeault S" first="Sophie L." last="Archambeault">Sophie L. Archambeault</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Abusin, Ghada" sort="Abusin, Ghada" uniqKey="Abusin G" first="Ghada" last="Abusin">Ghada Abusin</name><affiliation wicri:level="2"><nlm:aff id="A6">Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Iowa</region></placeName><wicri:cityArea>Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City</wicri:cityArea></affiliation></author><author><name sortKey="Beckman, Kyle" sort="Beckman, Kyle" uniqKey="Beckman K" first="Kyle" last="Beckman">Kyle Beckman</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Brown, Patrick A" sort="Brown, Patrick A" uniqKey="Brown P" first="Patrick A." last="Brown">Patrick A. Brown</name><affiliation wicri:level="2"><nlm:aff id="A7">Department of Pediatrics, The Johns Hopkins Hospital, Baltimore, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Pediatrics, The Johns Hopkins Hospital, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Briones, Michael" sort="Briones, Michael" uniqKey="Briones M" first="Michael" last="Briones">Michael Briones</name><affiliation wicri:level="2"><nlm:aff id="A8">Department of Pediatrics, Emory University School of Medicine, Aflac Cancer and Blood Disorder Center, Atlanta, GA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Department of Pediatrics, Emory University School of Medicine, Aflac Cancer and Blood Disorder Center, Atlanta</wicri:cityArea></affiliation></author><author><name sortKey="Carcamo, Benjamin" sort="Carcamo, Benjamin" uniqKey="Carcamo B" first="Benjamin" last="Carcamo">Benjamin Carcamo</name><affiliation wicri:level="2"><nlm:aff id="A9">Department of Pediatrics, Texas Tech University, El Paso, TX</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Department of Pediatrics, Texas Tech University, El Paso</wicri:cityArea></affiliation></author><author><name sortKey="Cooper, Todd" sort="Cooper, Todd" uniqKey="Cooper T" first="Todd" last="Cooper">Todd Cooper</name><affiliation wicri:level="2"><nlm:aff id="A10">Department of Pediatrics, Seattle Children's Hospital, Seattle, WA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Washington (État)</region></placeName><wicri:cityArea>Department of Pediatrics, Seattle Children's Hospital, Seattle</wicri:cityArea></affiliation></author><author><name sortKey="Dahl, Gary V" sort="Dahl, Gary V" uniqKey="Dahl G" first="Gary V." last="Dahl">Gary V. Dahl</name><affiliation wicri:level="2"><nlm:aff id="A11">Department of Pediatrics, Stanford School of Medicine, Stanford, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Stanford School of Medicine, Stanford</wicri:cityArea></affiliation></author><author><name sortKey="Emanuel, Peter D" sort="Emanuel, Peter D" uniqKey="Emanuel P" first="Peter D." last="Emanuel">Peter D. Emanuel</name><affiliation wicri:level="2"><nlm:aff id="A12">Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Arkansas</region></placeName><wicri:cityArea>Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock</wicri:cityArea></affiliation></author><author><name sortKey="Fluchel, Mark N" sort="Fluchel, Mark N" uniqKey="Fluchel M" first="Mark N." last="Fluchel">Mark N. Fluchel</name><affiliation wicri:level="2"><nlm:aff id="A13">Department of Pediatric Hematology Oncology, University of Utah, Salt Lake City, UT</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Utah</region></placeName><wicri:cityArea>Department of Pediatric Hematology Oncology, University of Utah, Salt Lake City</wicri:cityArea></affiliation></author><author><name sortKey="Goyal, Rakesh K" sort="Goyal, Rakesh K" uniqKey="Goyal R" first="Rakesh K." last="Goyal">Rakesh K. Goyal</name><affiliation wicri:level="2"><nlm:aff id="A14">Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh</wicri:cityArea></affiliation></author><author><name sortKey="Hayashi, Robert J" sort="Hayashi, Robert J" uniqKey="Hayashi R" first="Robert J." last="Hayashi">Robert J. Hayashi</name><affiliation wicri:level="2"><nlm:aff id="A15">Department of Pediatrics, Washington University School of Medicine, St. Louis, MO</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Missouri (État)</region></placeName><wicri:cityArea>Department of Pediatrics, Washington University School of Medicine, St. Louis</wicri:cityArea></affiliation></author><author><name sortKey="Hitzler, Johann" sort="Hitzler, Johann" uniqKey="Hitzler J" first="Johann" last="Hitzler">Johann Hitzler</name><affiliation wicri:level="1"><nlm:aff id="A16">Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Hugge, Christopher" sort="Hugge, Christopher" uniqKey="Hugge C" first="Christopher" last="Hugge">Christopher Hugge</name><affiliation wicri:level="2"><nlm:aff id="A17">Pediatric Hematology Oncology, SSM Cardinal Glennon Children's Medical Center, Saint Louis, MO</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Missouri (État)</region></placeName><wicri:cityArea>Pediatric Hematology Oncology, SSM Cardinal Glennon Children's Medical Center, Saint Louis</wicri:cityArea></affiliation></author><author><name sortKey="Liu, Y Lucy" sort="Liu, Y Lucy" uniqKey="Liu Y" first="Y. Lucy" last="Liu">Y. Lucy Liu</name><affiliation wicri:level="2"><nlm:aff id="A12">Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Arkansas</region></placeName><wicri:cityArea>Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock</wicri:cityArea></affiliation></author><author><name sortKey="Messinger, Yoav H" sort="Messinger, Yoav H" uniqKey="Messinger Y" first="Yoav H." last="Messinger">Yoav H. Messinger</name><affiliation wicri:level="2"><nlm:aff id="A18">Division of Pediatric Hematology Oncology, Children's Hospitals and Clinics of Minnesota, Minneapolis, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Division of Pediatric Hematology Oncology, Children's Hospitals and Clinics of Minnesota, Minneapolis</wicri:cityArea></affiliation></author><author><name sortKey="Mahoney, Donald H" sort="Mahoney, Donald H" uniqKey="Mahoney D" first="Donald H." last="Mahoney">Donald H. Mahoney</name><affiliation wicri:level="2"><nlm:aff id="A19">Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston</wicri:cityArea></affiliation></author><author><name sortKey="Monteleone, Philip" sort="Monteleone, Philip" uniqKey="Monteleone P" first="Philip" last="Monteleone">Philip Monteleone</name><affiliation wicri:level="2"><nlm:aff id="A20">Pediatric Hematology Oncology, Pediatric Specialists of Lehigh Valley Hospital, Bethlehem, PA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Pediatric Hematology Oncology, Pediatric Specialists of Lehigh Valley Hospital, Bethlehem</wicri:cityArea></affiliation></author><author><name sortKey="Nemecek, Eneida R" sort="Nemecek, Eneida R" uniqKey="Nemecek E" first="Eneida R." last="Nemecek">Eneida R. Nemecek</name><affiliation wicri:level="2"><nlm:aff id="A21">Pediatric Bone Marrow Transplant Program, Oregon Health & Science University, Portland, OR</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Oregon</region></placeName><wicri:cityArea>Pediatric Bone Marrow Transplant Program, Oregon Health & Science University, Portland</wicri:cityArea></affiliation></author><author><name sortKey="Roehrs, Philip A" sort="Roehrs, Philip A" uniqKey="Roehrs P" first="Philip A." last="Roehrs">Philip A. Roehrs</name><affiliation wicri:level="2"><nlm:aff id="A22">Department of Pediatrics, University of North Carolina at Chapel Hill, NC</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Department of Pediatrics, University of North Carolina at Chapel Hill</wicri:cityArea></affiliation></author><author><name sortKey="Schore, Reuven J" sort="Schore, Reuven J" uniqKey="Schore R" first="Reuven J." last="Schore">Reuven J. Schore</name><affiliation wicri:level="2"><nlm:aff id="A23">Division of Pediatric Oncology, Children's National Medical Center, Washington, DC</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">District de Columbia</region></placeName><wicri:cityArea>Division of Pediatric Oncology, Children's National Medical Center, Washington</wicri:cityArea></affiliation></author><author><name sortKey="Stine, Kimo C" sort="Stine, Kimo C" uniqKey="Stine K" first="Kimo C." last="Stine">Kimo C. Stine</name><affiliation wicri:level="2"><nlm:aff id="A24">Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Arkansas</region></placeName><wicri:cityArea>Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock</wicri:cityArea></affiliation></author><author><name sortKey="Takemoto, Clifford M" sort="Takemoto, Clifford M" uniqKey="Takemoto C" first="Clifford M." last="Takemoto">Clifford M. Takemoto</name><affiliation wicri:level="2"><nlm:aff id="A7">Department of Pediatrics, The Johns Hopkins Hospital, Baltimore, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Pediatrics, The Johns Hopkins Hospital, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Toretsky, Jeffrey A" sort="Toretsky, Jeffrey A" uniqKey="Toretsky J" first="Jeffrey A." last="Toretsky">Jeffrey A. Toretsky</name><affiliation wicri:level="2"><nlm:aff id="A25">Department of Pediatrics, Georgetown University, Washington, DC</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">District de Columbia</region></placeName><wicri:cityArea>Department of Pediatrics, Georgetown University, Washington</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A26">Department of Oncology, Georgetown University, Washington, DC</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">District de Columbia</region></placeName><wicri:cityArea>Department of Oncology, Georgetown University, Washington</wicri:cityArea></affiliation></author><author><name sortKey="Costello, Joseph F" sort="Costello, Joseph F" uniqKey="Costello J" first="Joseph F." last="Costello">Joseph F. Costello</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Neurological Surgery, University of California, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Neurological Surgery, University of California, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Olshen, Adam B" sort="Olshen, Adam B" uniqKey="Olshen A" first="Adam B." last="Olshen">Adam B. Olshen</name><affiliation wicri:level="2"><nlm:aff id="A27">Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A28">Department of Epidemiology and Biostatistics, University of California, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Epidemiology and Biostatistics, University of California, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Stewart, Chip" sort="Stewart, Chip" uniqKey="Stewart C" first="Chip" last="Stewart">Chip Stewart</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Li, Yongjin" sort="Li, Yongjin" uniqKey="Li Y" first="Yongjin" last="Li">Yongjin Li</name><affiliation wicri:level="2"><nlm:aff id="A3">Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Computational Biology, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation></author><author><name sortKey="Ma, Jing" sort="Ma, Jing" uniqKey="Ma J" first="Jing" last="Ma">Jing Ma</name><affiliation wicri:level="2"><nlm:aff id="A29">Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Pathology, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation></author><author><name sortKey="Gerbing, Robert B" sort="Gerbing, Robert B" uniqKey="Gerbing R" first="Robert B." last="Gerbing">Robert B. Gerbing</name><affiliation wicri:level="2"><nlm:aff id="A30">Department of Statistics, Children's Oncology Group, Monrovia, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Statistics, Children's Oncology Group, Monrovia</wicri:cityArea></affiliation></author><author><name sortKey="Alonzo, Todd A" sort="Alonzo, Todd A" uniqKey="Alonzo T" first="Todd A." last="Alonzo">Todd A. Alonzo</name><affiliation wicri:level="2"><nlm:aff id="A31">Keck School of Medicine, University of Southern California, Los Angeles, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Keck School of Medicine, University of Southern California, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Getz, Gad" sort="Getz, Gad" uniqKey="Getz G" first="Gad" last="Getz">Gad Getz</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A32">Harvard Medical School, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Harvard Medical School, Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A33">Department of Pathology and Cancer Center, Massachusetts General Hospital, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Pathology and Cancer Center, Massachusetts General Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Gruber, Tanja" sort="Gruber, Tanja" uniqKey="Gruber T" first="Tanja" last="Gruber">Tanja Gruber</name><affiliation wicri:level="2"><nlm:aff id="A29">Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Pathology, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A34">Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Tennessee</region></placeName><wicri:cityArea>Department of Oncology, St. Jude Children's Research Hospital, Memphis</wicri:cityArea></affiliation></author><author><name sortKey="Golub, Todd" sort="Golub, Todd" uniqKey="Golub T" first="Todd" last="Golub">Todd Golub</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A35">Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A36">Division of Hematology/Oncology, Boston Children's Hospital and Harvard Medical School, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Hematology/Oncology, Boston Children's Hospital and Harvard Medical School, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Stegmaier, Kimberly" sort="Stegmaier, Kimberly" uniqKey="Stegmaier K" first="Kimberly" last="Stegmaier">Kimberly Stegmaier</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of MIT and Harvard, Cambridge, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Broad Institute of MIT and Harvard, Cambridge</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A35">Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A36">Division of Hematology/Oncology, Boston Children's Hospital and Harvard Medical School, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Hematology/Oncology, Boston Children's Hospital and Harvard Medical School, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Loh, Mignon L" sort="Loh, Mignon L" uniqKey="Loh M" first="Mignon L." last="Loh">Mignon L. Loh</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A37">Department of Pediatrics, Benioff Children's Hospital, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Pediatrics, Benioff Children's Hospital, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco</wicri:cityArea></affiliation></author></analytic><series><title level="j">Nature genetics</title><idno type="ISSN">1061-4036</idno><idno type="eISSN">1546-1718</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative neoplasm (MPN) of childhood with a poor prognosis. Mutations in <italic>NF1, NRAS, KRAS, PTPN11</italic> and <italic>CBL</italic> occur in 85% of patients, yet there are currently no risk stratification algorithms capable of predicting which patients will be refractory to conventional treatment and therefore be candidates for experimental therapies. In addition, there have been few other molecular pathways identified aside from the Ras/MAPK pathway to serve as the basis for such novel therapeutic strategies. We therefore sought to genomically characterize serial samples from patients at diagnosis through relapse and transformation to acute myeloid leukemia in order to expand our knowledge of the mutational spectrum in JMML. We identified recurrent mutations in genes involved in signal transduction, gene splicing, the polycomb repressive complex 2 (PRC2) and transcription. Importantly, the number of somatic alterations present at diagnosis appears to be the major determinant of outcome.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Chang, Ty" uniqKey="Chang T">TY Chang</name></author><author><name sortKey="Dvorak, Cc" uniqKey="Dvorak C">CC Dvorak</name></author><author><name sortKey="Loh, Ml" uniqKey="Loh M">ML Loh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dvorak, Cc" uniqKey="Dvorak C">CC Dvorak</name></author><author><name sortKey="Loh, Ml" uniqKey="Loh M">ML Loh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Matsuda, K" uniqKey="Matsuda K">K Matsuda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Matsuda, K" uniqKey="Matsuda K">K Matsuda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bresolin, S" uniqKey="Bresolin S">S Bresolin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Flotho, C" uniqKey="Flotho C">C Flotho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Side, L" uniqKey="Side L">L Side</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Flotho, C" uniqKey="Flotho C">C Flotho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tartaglia, M" uniqKey="Tartaglia M">M Tartaglia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Loh, Ml" uniqKey="Loh M">ML Loh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Loh, Ml" uniqKey="Loh M">ML Loh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sakaguchi, H" uniqKey="Sakaguchi H">H Sakaguchi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stieglitz, E" uniqKey="Stieglitz E">E Stieglitz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Niemeyer, Cm" uniqKey="Niemeyer C">CM Niemeyer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stephens, K" uniqKey="Stephens K">K Stephens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Flex, E" uniqKey="Flex E">E Flex</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Graham, Sm" uniqKey="Graham S">SM Graham</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Patmore, Dm" uniqKey="Patmore D">DM Patmore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, Am" uniqKey="Chan A">AM Chan</name></author><author><name sortKey="Miki, T" uniqKey="Miki T">T Miki</name></author><author><name sortKey="Meyers, Ka" uniqKey="Meyers K">KA Meyers</name></author><author><name sortKey="Aaronson, Sa" uniqKey="Aaronson S">SA Aaronson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Locatelli, F" uniqKey="Locatelli F">F Locatelli</name></author><author><name sortKey="Niemeyer, Cm" uniqKey="Niemeyer C">CM Niemeyer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tinschert, S" uniqKey="Tinschert S">S Tinschert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Side, Le" uniqKey="Side L">LE Side</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kotecha, N" uniqKey="Kotecha N">N Kotecha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rudd, Ce" uniqKey="Rudd C">CE Rudd</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oh, St" uniqKey="Oh S">ST Oh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lasho, Tl" uniqKey="Lasho T">TL Lasho</name></author><author><name sortKey="Pardanani, A" uniqKey="Pardanani A">A Pardanani</name></author><author><name sortKey="Tefferi, A" uniqKey="Tefferi A">A Tefferi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hurtado, C" uniqKey="Hurtado C">C Hurtado</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Perez Garcia, A" uniqKey="Perez Garcia A">A Perez-Garcia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcmullin, Mf" uniqKey="Mcmullin M">MF McMullin</name></author><author><name sortKey="Wu, C" uniqKey="Wu C">C Wu</name></author><author><name sortKey="Percy, Mj" uniqKey="Percy M">MJ Percy</name></author><author><name sortKey="Tong, W" uniqKey="Tong W">W Tong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gambacorti Passerini, Cb" uniqKey="Gambacorti Passerini C">CB Gambacorti-Passerini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, Z" uniqKey="Yang Z">Z Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pasquet, M" uniqKey="Pasquet M">M Pasquet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kazenwadel, J" uniqKey="Kazenwadel J">J Kazenwadel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hsu, Ap" uniqKey="Hsu A">AP Hsu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hahn, Cn" uniqKey="Hahn C">CN Hahn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ostergaard, P" uniqKey="Ostergaard P">P Ostergaard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stieglitz, E" uniqKey="Stieglitz E">E Stieglitz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fasan, A" uniqKey="Fasan A">A Fasan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Papaemmanuil, E" uniqKey="Papaemmanuil E">E Papaemmanuil</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bauer, De" uniqKey="Bauer D">DE Bauer</name></author><author><name sortKey="Loh, Ml" uniqKey="Loh M">ML Loh</name></author><author><name sortKey="Bhagat, G" uniqKey="Bhagat G">G Bhagat</name></author><author><name sortKey="Cantor, Ab" uniqKey="Cantor A">AB Cantor</name></author><author><name sortKey="Kung, Al" uniqKey="Kung A">AL Kung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Osato, M" uniqKey="Osato M">M Osato</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sano, H" uniqKey="Sano H">H Sano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yoshimi, A" uniqKey="Yoshimi A">A Yoshimi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albert, Mh" uniqKey="Albert M">MH Albert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Perez, B" uniqKey="Perez B">B Perez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sugimoto, Y" uniqKey="Sugimoto Y">Y Sugimoto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kar, Sa" uniqKey="Kar S">SA Kar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ribeiro, Af" uniqKey="Ribeiro A">AF Ribeiro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ley, Tj" uniqKey="Ley T">TJ Ley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Madan, V" uniqKey="Madan V">V Madan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hirabayashi, S" uniqKey="Hirabayashi S">S Hirabayashi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Takita, J" uniqKey="Takita J">J Takita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jankowska, Am" uniqKey="Jankowska A">AM Jankowska</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Furlan, I" uniqKey="Furlan I">I Furlan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Russler Germain, Da" uniqKey="Russler Germain D">DA Russler-Germain</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Archambeault, S" uniqKey="Archambeault S">S Archambeault</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kothari, A" uniqKey="Kothari A">A Kothari</name></author><author><name sortKey="Hulbert, Ml" uniqKey="Hulbert M">ML Hulbert</name></author><author><name sortKey="Cottrell, Ce" uniqKey="Cottrell C">CE Cottrell</name></author><author><name sortKey="Nguyen, Tt" uniqKey="Nguyen T">TT Nguyen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, Ml" uniqKey="Lee M">ML Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Greaves, M" uniqKey="Greaves M">M Greaves</name></author><author><name sortKey="Maley, Cc" uniqKey="Maley C">CC Maley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chang, T" uniqKey="Chang T">T Chang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lyubynska, N" uniqKey="Lyubynska N">N Lyubynska</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, Rj" uniqKey="Chan R">RJ Chan</name></author><author><name sortKey="Cooper, T" uniqKey="Cooper T">T Cooper</name></author><author><name sortKey="Kratz, Cp" uniqKey="Kratz C">CP Kratz</name></author><author><name sortKey="Weiss, B" uniqKey="Weiss B">B Weiss</name></author><author><name sortKey="Loh, Ml" uniqKey="Loh M">ML Loh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stieglitz, E" uniqKey="Stieglitz E">E Stieglitz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cibulskis, K" uniqKey="Cibulskis K">K Cibulskis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Depristo, Ma" uniqKey="Depristo M">MA DePristo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mckenna, A" uniqKey="Mckenna A">A McKenna</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chapman, Ma" uniqKey="Chapman M">MA Chapman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Venkatraman, Es" uniqKey="Venkatraman E">ES Venkatraman</name></author><author><name sortKey="Olshen, Ab" uniqKey="Olshen A">AB Olshen</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Reva, B" uniqKey="Reva B">B Reva</name></author><author><name sortKey="Antipin, Y" uniqKey="Antipin Y">Y Antipin</name></author><author><name sortKey="Sander, C" uniqKey="Sander C">C Sander</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Forbes, Sa" uniqKey="Forbes S">SA Forbes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Triche, Tj" uniqKey="Triche T">TJ Triche</name></author><author><name sortKey="Weisenberger, Dj" uniqKey="Weisenberger D">DJ Weisenberger</name></author><author><name sortKey="Van Den Berg, D" uniqKey="Van Den Berg D">D Van Den Berg</name></author><author><name sortKey="Laird, Pw" uniqKey="Laird P">PW Laird</name></author><author><name sortKey="Siegmund, Kd" uniqKey="Siegmund K">KD Siegmund</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Dulak, Am" uniqKey="Dulak A">AM Dulak</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Trapnell, C" uniqKey="Trapnell C">C Trapnell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Trapnell, C" uniqKey="Trapnell C">C Trapnell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kaplan, El" uniqKey="Kaplan E">EL Kaplan</name></author><author><name sortKey="Meier, P" uniqKey="Meier P">P Meier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cox, Dr" uniqKey="Cox D">DR Cox</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gray, Rj" uniqKey="Gray R">RJ Gray</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Canada</li><li>États-Unis</li></country><region><li>Arkansas</li><li>Californie</li><li>Caroline du Nord</li><li>District de Columbia</li><li>Géorgie (États-Unis)</li><li>Iowa</li><li>Massachusetts</li><li>Minnesota</li><li>Missouri (État)</li><li>Oregon</li><li>Pennsylvanie</li><li>Tennessee</li><li>Texas</li><li>Utah</li><li>Washington (État)</li></region></list><tree><country name="États-Unis"><region name="Californie"><name sortKey="Stieglitz, Elliot" sort="Stieglitz, Elliot" uniqKey="Stieglitz E" first="Elliot" last="Stieglitz">Elliot Stieglitz</name></region><name sortKey="Abusin, Ghada" sort="Abusin, Ghada" uniqKey="Abusin G" first="Ghada" last="Abusin">Ghada Abusin</name><name sortKey="Alonzo, Todd A" sort="Alonzo, Todd A" uniqKey="Alonzo T" first="Todd A." last="Alonzo">Todd A. Alonzo</name><name sortKey="Archambeault, Sophie L" sort="Archambeault, Sophie L" uniqKey="Archambeault S" first="Sophie L." last="Archambeault">Sophie L. Archambeault</name><name sortKey="Beckman, Kyle" sort="Beckman, Kyle" uniqKey="Beckman K" first="Kyle" last="Beckman">Kyle Beckman</name><name sortKey="Briones, Michael" sort="Briones, Michael" uniqKey="Briones M" first="Michael" last="Briones">Michael Briones</name><name sortKey="Brown, Patrick A" sort="Brown, Patrick A" uniqKey="Brown P" first="Patrick A." last="Brown">Patrick A. Brown</name><name sortKey="Carcamo, Benjamin" sort="Carcamo, Benjamin" uniqKey="Carcamo B" first="Benjamin" last="Carcamo">Benjamin Carcamo</name><name sortKey="Chang, Tiffany Y" sort="Chang, Tiffany Y" uniqKey="Chang T" first="Tiffany Y." last="Chang">Tiffany Y. Chang</name><name sortKey="Cooper, Todd" sort="Cooper, Todd" uniqKey="Cooper T" first="Todd" last="Cooper">Todd Cooper</name><name sortKey="Costello, Joseph F" sort="Costello, Joseph F" uniqKey="Costello J" first="Joseph F." last="Costello">Joseph F. Costello</name><name sortKey="Dahl, Gary V" sort="Dahl, Gary V" uniqKey="Dahl G" first="Gary V." last="Dahl">Gary V. Dahl</name><name sortKey="Emanuel, Peter D" sort="Emanuel, Peter D" uniqKey="Emanuel P" first="Peter D." last="Emanuel">Peter D. Emanuel</name><name sortKey="Esquivel, Emilio" sort="Esquivel, Emilio" uniqKey="Esquivel E" first="Emilio" last="Esquivel">Emilio Esquivel</name><name sortKey="Fluchel, Mark N" sort="Fluchel, Mark N" uniqKey="Fluchel M" first="Mark N." last="Fluchel">Mark N. Fluchel</name><name sortKey="Gelston, Laura C" sort="Gelston, Laura C" uniqKey="Gelston L" first="Laura C." last="Gelston">Laura C. Gelston</name><name sortKey="Gerbing, Robert B" sort="Gerbing, Robert B" uniqKey="Gerbing R" first="Robert B." last="Gerbing">Robert B. Gerbing</name><name sortKey="Getz, Gad" sort="Getz, Gad" uniqKey="Getz G" first="Gad" last="Getz">Gad Getz</name><name sortKey="Getz, Gad" sort="Getz, Gad" uniqKey="Getz G" first="Gad" last="Getz">Gad Getz</name><name sortKey="Getz, Gad" sort="Getz, Gad" uniqKey="Getz G" first="Gad" last="Getz">Gad Getz</name><name sortKey="Golub, Todd" sort="Golub, Todd" uniqKey="Golub T" first="Todd" last="Golub">Todd Golub</name><name sortKey="Golub, Todd" sort="Golub, Todd" uniqKey="Golub T" first="Todd" last="Golub">Todd Golub</name><name sortKey="Golub, Todd" sort="Golub, Todd" uniqKey="Golub T" first="Todd" last="Golub">Todd Golub</name><name sortKey="Goyal, Rakesh K" sort="Goyal, Rakesh K" uniqKey="Goyal R" first="Rakesh K." last="Goyal">Rakesh K. Goyal</name><name sortKey="Gruber, Tanja" sort="Gruber, Tanja" uniqKey="Gruber T" first="Tanja" last="Gruber">Tanja Gruber</name><name sortKey="Gruber, Tanja" sort="Gruber, Tanja" uniqKey="Gruber T" first="Tanja" last="Gruber">Tanja Gruber</name><name sortKey="Hayashi, Robert J" sort="Hayashi, Robert J" uniqKey="Hayashi R" first="Robert J." last="Hayashi">Robert J. Hayashi</name><name sortKey="Hugge, Christopher" sort="Hugge, Christopher" uniqKey="Hugge C" first="Christopher" last="Hugge">Christopher Hugge</name><name sortKey="Li, Yongjin" sort="Li, Yongjin" uniqKey="Li Y" first="Yongjin" last="Li">Yongjin Li</name><name sortKey="Liu, Y Lucy" sort="Liu, Y Lucy" uniqKey="Liu Y" first="Y. Lucy" last="Liu">Y. Lucy Liu</name><name sortKey="Loh, Mignon L" sort="Loh, Mignon L" uniqKey="Loh M" first="Mignon L." last="Loh">Mignon L. Loh</name><name sortKey="Loh, Mignon L" sort="Loh, Mignon L" uniqKey="Loh M" first="Mignon L." last="Loh">Mignon L. Loh</name><name sortKey="Ma, Jing" sort="Ma, Jing" uniqKey="Ma J" first="Jing" last="Ma">Jing Ma</name><name sortKey="Mahoney, Donald H" sort="Mahoney, Donald H" uniqKey="Mahoney D" first="Donald H." last="Mahoney">Donald H. Mahoney</name><name sortKey="Mazor, Tali" sort="Mazor, Tali" uniqKey="Mazor T" first="Tali" last="Mazor">Tali Mazor</name><name sortKey="Messinger, Yoav H" sort="Messinger, Yoav H" uniqKey="Messinger Y" first="Yoav H." last="Messinger">Yoav H. Messinger</name><name sortKey="Monteleone, Philip" sort="Monteleone, Philip" uniqKey="Monteleone P" first="Philip" last="Monteleone">Philip Monteleone</name><name sortKey="Nemecek, Eneida R" sort="Nemecek, Eneida R" uniqKey="Nemecek E" first="Eneida R." last="Nemecek">Eneida R. Nemecek</name><name sortKey="Olsen, Scott" sort="Olsen, Scott" uniqKey="Olsen S" first="Scott" last="Olsen">Scott Olsen</name><name sortKey="Olshen, Adam B" sort="Olshen, Adam B" uniqKey="Olshen A" first="Adam B." last="Olshen">Adam B. Olshen</name><name sortKey="Olshen, Adam B" sort="Olshen, Adam B" uniqKey="Olshen A" first="Adam B." last="Olshen">Adam B. Olshen</name><name sortKey="Roehrs, Philip A" sort="Roehrs, Philip A" uniqKey="Roehrs P" first="Philip A." last="Roehrs">Philip A. Roehrs</name><name sortKey="Rosenberg, Mara" sort="Rosenberg, Mara" uniqKey="Rosenberg M" first="Mara" last="Rosenberg">Mara Rosenberg</name><name sortKey="Schore, Reuven J" sort="Schore, Reuven J" uniqKey="Schore R" first="Reuven J." last="Schore">Reuven J. Schore</name><name sortKey="Seepo, Sara" sort="Seepo, Sara" uniqKey="Seepo S" first="Sara" last="Seepo">Sara Seepo</name><name sortKey="Stegmaier, Kimberly" sort="Stegmaier, Kimberly" uniqKey="Stegmaier K" first="Kimberly" last="Stegmaier">Kimberly Stegmaier</name><name sortKey="Stegmaier, Kimberly" sort="Stegmaier, Kimberly" uniqKey="Stegmaier K" first="Kimberly" last="Stegmaier">Kimberly Stegmaier</name><name sortKey="Stegmaier, Kimberly" sort="Stegmaier, Kimberly" uniqKey="Stegmaier K" first="Kimberly" last="Stegmaier">Kimberly Stegmaier</name><name sortKey="Stewart, Chip" sort="Stewart, Chip" uniqKey="Stewart C" first="Chip" last="Stewart">Chip Stewart</name><name sortKey="Stine, Kimo C" sort="Stine, Kimo C" uniqKey="Stine K" first="Kimo C." last="Stine">Kimo C. Stine</name><name sortKey="Takemoto, Clifford M" sort="Takemoto, Clifford M" uniqKey="Takemoto C" first="Clifford M." last="Takemoto">Clifford M. Takemoto</name><name sortKey="Taylor Weiner, Amaro N" sort="Taylor Weiner, Amaro N" uniqKey="Taylor Weiner A" first="Amaro N." last="Taylor-Weiner">Amaro N. Taylor-Weiner</name><name sortKey="Toretsky, Jeffrey A" sort="Toretsky, Jeffrey A" uniqKey="Toretsky J" first="Jeffrey A." last="Toretsky">Jeffrey A. Toretsky</name><name sortKey="Toretsky, Jeffrey A" sort="Toretsky, Jeffrey A" uniqKey="Toretsky J" first="Jeffrey A." last="Toretsky">Jeffrey A. Toretsky</name><name sortKey="Wang, Yong Dong" sort="Wang, Yong Dong" uniqKey="Wang Y" first="Yong-Dong" last="Wang">Yong-Dong Wang</name><name sortKey="Yu, Ariel" sort="Yu, Ariel" uniqKey="Yu A" first="Ariel" last="Yu">Ariel Yu</name></country><country name="Canada"><noRegion><name sortKey="Hitzler, Johann" sort="Hitzler, Johann" uniqKey="Hitzler J" first="Johann" last="Hitzler">Johann Hitzler</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001755 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001755 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:4626387
|texte= The Genomic Landscape of Juvenile Myelomonocytic Leukemia
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:26457647" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |